Co-Q10

Many Researchers Call Co-Enzyme Q10 "The Miracle Nutrient"

Co-Q10 Is Essential to Life and Critical in Energy Production (1)

Co-Enzyme Q10, also known as CoQ or ubiquinone, is an important vitamin-like nutrient referred to by some researchers as "the miracle nutrient" and "the nutrient of the 90's" because of the positive results seen in research done with a variety of diseases and conditions.
Co-Q10 resembles vitamin E and vitamin K in chemical structure. Biochemically it functions much like vitamin E in that it participates in anti-oxidant and free radical reactions. However, Co-Q10 has a special biochemical role of major importance...it plays a critical role in the production of ATP, the basic energy molecule of all cells.
Co-Enzyme Q10 is essential to life. According to projections based on autopsies of diseased human hearts and biopsies from healthy hearts and other organ and tissue samples, once internal levels of Co-Q1O drop below 25% of normal, disease is likely to ensue. If levels drop to a 75% deficiency, death will probably follow as a natural course.

Anti-Aging/Life Extension Seen with Co-Q1O supplementation (1)

Although the body can absorb C-Q10 from foods or synthesize the nutrient from other co-enzymes (Q1 through Q9) that ability declines through the normal process of aging as do body levels of Co-Q10. Restoration of youthful Co-Q10 levels through supplementation has been shown to correct many diseases associated with the aging process.
Animal studies by Dr. Emile Bliznakov, scientific director of the Lupus Research institute in Ridge-field, CT, have shown that the mean life span can be increased by as much as 50% through Co-Q10 supplementation. More importantly, the longer living animals remained more active and younger looking with bright eyes, glossy coats and healthy skin. And, their more youthful appearance lasted right up to the end of their lives.

Most Heart Patients Show Significant Co-Q10 Deficiency (1,4)

More Co-Q10 is found in the heart tissue than in any other muscle in the body. According to Dr. Karl Folkers, the "father" of C-Q10 research in the United States, most heart patients show a significant deficiency of Co-Q10. Research, conducted by Dr. Folkers and confirmed by numerous other re-searchers around the world, has shown remarkable improvement in patients suffering from congestive heart failure, myocardial ischemic disorder and angina pectoris when given supplements of Co-Q10. Co-Q10 has also been shown to have a stabilizing effect on heart rhythm. Dr. Folkers believes that Co-Q10 deficiency may even be a major cause of heart disease and that prophylactic use of the nutrient may prevent many human heart problems.

Co-Q10 Reverses Hypertension (1,3)

Although the role of Co-Q10 in the normalization of blood pressure is not fully understood, animal and clinical studies have shown that the nutrient can, indeed, lower elevated blood pressure.
A distinct connection has been observed between Co-Q10 deficiencies as well as elevated ratio of sodium to potassium in the blood and tissues of high blood pressure patients. With Co-Q10 therapy, the ratio of sodium to potassium decreases. This action is much like the beneficial effect seen when high blood pressure patients remove salt (sodium) from their diets.
Tests also show that Co-Q10 supplementation has no effect at all on blood pressure levels of individuals with normal blood pressure.

Revitalizing the Immune System (1,2)

Scientist now attach crucial importance to the link between the immune system and aging. A series of experiments by Bliznakov and others show that Co-Q10 supplementation can:
* Double the immune system's ability to clear invading organisms from the blood.
* Double antibody levels.
* Protect against chemically induced cancer (fewer and smaller tumors and increased survival times).
* increase resistance to viral infections.
* Reduce the toxicity? of immunosuppressive drugs used in cancer treatment.
* Quench free radicals associated with arthritis and other chronic degenerative diseases.

The importance of stimulating the immune system cannot be overstated. A strong immune system can protect us from many diseases, from colds to cancer.
Impressive new Co-Q10 research involves not only the immune system -- with diseases such as diabetes, muscular dystrophy1 multiple sclerosis and lupus erythematosus -- it also involves Co-Q10's beneficial role in treating allergies, asthma and other respiratory conditions as well as potential for treating anomalies of mental function such as schizophrenia and even Alzheimer's disease.

Periodontal (Gum) Disease Responds Dramatically to Co-Q10(1 ,5)

One in four people in the United States will lose all their teeth to periodontal disease by age 60 and 90% of all Americans will suffer from it during their lifetimes. Studies conducted by Dr. Karl Folkers of the University of Texas and periodontal specialist Dr. Edward C. Wilkinson have shown that, unlike healthy oral tissue, cells in victims of periodontal disease were markedly deficient in Co-Q10.
When Co-Q10 was added to the diets of patients suffering from periodontal conditions, some resuits were dramatic. Not only was the progression of the disease halted, but also guns that were once diseased and bleeding began to show clinically significant reversal of the disease process.
One case history involved an elderly woman who had not been able to eat solid foods for months because of intense pain. She was a "no hope" case. After 14 days of Co-Q10 supplementation, the pain diminished and she was eating solids. Three months later her gums were a healthy pink and showed an almost complete reversal of the disease state.

Co-Q10 Affects Energy, Metabolism and Storage of Body Fat (1,6)

Recent research into the causes of obesity has shown that one factor affecting metabolic rate is the amount of body heat generating brown adipose (fat) tissue. Thin people seem to waste more calories as heat while fat people tend to efficiently conserve calories and store them as fat. Since Co-Q10 is critical to cell energy production and, thus, the production of body heat, it is reasonable to expect that body Co-Q10 levels affect the storage of body fat.
Clearly, Co-Q10 is a weight-loss aid to those who are deficient in the nutrient. In a Belgian study of 27 obese patients, Dr. Luc Van Gaal found that over half of the persons studied were significantly deficient in Co-Q10. Dr. Van Gaal and his co1leagues then performed a clinical study on two groups of overweight subjects. Subjects in group A were found to be deficient in Co-Q10 while subjects in group B were not. Both groups were placed on controlled reducing diets and both were given 100 mg. of Co-Q10 daily. After 9 weeks Group A had lost an average of 30 pounds compared to an average of 13 pounds for group B. After 3 months the Co-Q10 deficient group had lost an average of 38 pounds.
Because Co-Q10 is intimately involved with energy production, it is not surprising that body builders and other athletes have reported benefits. In a test involving sedentary young men on an exercise bike, performance parameters increased 12% for medium heart stress conditions to 28% for maximal heart stress after 8 weeks of Co-Q10 supplementation and there was even significant improvement in resting heart function. Several performance parameters were measured including work capacity, maximal oxygen consumption and oxygen transport. No changes were made in the men's diet or exercise habits other than the Co-Q10 supplementation.

WARNING: The products listed in this publication can not under any circumstances be considered as treatment, cure, prevention or therapy, or as the only treatment or therapy for any disease or condition Nor can the products under any circumstances be considered as a substitute or alternative treatment or therapy for any disease or condition. The products contained in this publication have not been approved or evaluated by the Federal Drug Administration. These publications, and the products contained herein, are not intended to diagnose, treat, cure or prevent any disease or condition. The products relate to nutritional support only.

REFERENCES.

1. Blianakof, E., Hunt, C., The Miracle Nutrient Coenzyme Q10, Bantam, 1987. Fahy, G.M., Life Extension Benefits of Coenzyme Q1O, Antiaging News, Vol.3, No.7, pp. 74-8, July 1983.
Folkers, K, et al., Biomedical and clinical Aspects of Coenzyme Q. (Vols. 1-4), Elsevier Science Publishers, 1977,1980,1981,1984.
Passwater, R., Coenzyme Q1O: The Nutrient of the 90's, Whole Foods, April, 1987.
2. Bliznakov, E.G., Casey, A. and Premuzic, E, Coenzymes Q: Stimulants of Phagocytic Activity in Rats and Immune Response in Mice. Experientia, Vol.26, pp.9534, 1970.
Downs, L, Coenzyme Q1O, Bestways, June 1987.
3. Yarnasami, T., Shibata, N., Folkers, K., "Bloenergetics in Clinical Medicine. Studies on coenzyme Q1O and essential hypertension", Res. commun. Chem. Pathol. Pharmacol., 2:23748,1975.
4. Folkers, K., Sartoti, M., Baker, L. and Richardson, P., Observations of Significant Reductions of Arrhythrnias in Treatment with Coenzyme Q1O of Patients Having cardiovascular Disease. IRCS Medical Science 10, pp.348-349, 1982.
Folkers, K., Vadinnavikit, S. and Mortensen, S.A., Biochemical Rationale and Myocardial Tissue Data on the Effective Therapy of Cardiomyopathy and Coenzyme Q1O. Ptoc. Natl Acad. Sci., Vol.62, pp. 901-4, Feb. 1985
Hunt, G.L., Miracle Nutrient? Omni Magazine, Feb. 1987.
Langsjoen, P., Proceed. Nat. Acad. SCL 82:424044, June 1985.
5. Wilkinson, E., Arnold, R., Folkers, K., "Bioenergetics in Clinical Medicine VIII. Adjunctive Treatment of Periodontal Disease with Co-Enzyme Q1O", Res. Commun Chem. Pathol Pharmacol, 4:711-9,1976.
6. Van Gaal, L., DeLesuw, L, Vadhanavlkit, S., Polkers, K., Exploratory Study of Coenzyme Q10 in Obesity. Biomedical and Clinical Aspects of Coenzyme Q, Vol.4, pp.369-73, Elsevier Science Publishers B.V., 1984.

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